Most of you will not be aware of what is Oral Lichen Planus. So let’s start with its introduction. The historical features of the Oral Lichen Planus were first described by Dubreuil in the year 1906. Lichen Planus is the common mucocutaneous disease that affects the skin and areas in the oral cavity. Here In this article you will get a glimpse of research done on “Analysis of the changes in the basal cell region of oral lichen planus” by Maurya Paul from Department of Oral Pathology, Inderprastha Dental College and Hospital, Sahibabad, Ghaziabad, India and Dr Devicharan Shetty, ITS Dental College, Muradnagar, Ghaziabad, India. Their research paper was published on 18-April-2013.
This Lesion at first was described by Wilson in 1869 and then he compared skin lesions of lichen planus to lichens (fungi or algae) that grow on flat rocks. This characteristic appearance gave rise to the advent of term “lichen planus”.
The aim of this study done by Dr DC Shetty and Maurya Paul is that “By studying OLP electron microscopically we shall be emphasising on cells and its interactions in specified surroundings that would help us in hypothesising the effects of its specific cell-to-cell interactions.”
The study was started by selecting 20 cases of oral lichen planus and then categorised them into erosive and non-erosive forms on the basis of their clinical pattern and then confirmed them as lichen planus by histopathological analysis. After all the research work is being done then in results basal cells showed the regular stratification in normal epithelium. Many other changes and results were found after the tests. The results also became very clear with the figures that were obtained while the study was carried out by Dr Shetty and Maurya Paul. All the other results can be found in the publication that is being published. The present study confirms that the structural findings of the basal cells in OLP with the previous author’s findings. Also, categorization of ultrastructural differences between the erosive and non-erosive lichen planus has raised the question of the difference in the probable cellular and molecular mechanism between the erosive and non-erosive forms. As per the research paper that is published, the findings of the present study are concurrent with the previous studies and it could be used as a basis on which the studies related to the molecular studies could be paralleled. This could also help to bring in unison to the various theories postulated on the pathogenesis of OLP.